CMiST, Center for Microbiome Sciences & Therapeutics, will serve as a hub of collaboration and connectivity for researchers and clinicians at the University of Washington and its affiliated campuses.

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To be the foremost leader in microbiome research throughout the Pacific Northwest region known for our thoughtful collaborations, our unique approach to experimental design and our dedication to educating the community about the importance of the microbiome in maintaining a healthy lifestyle.



Think Deeply

Too often the road with the least resistance is taken, but true innovation means looking past the obvious and not accepting answers at face value. Being able to think deeply means being open to all possibilities, thinking outside of the box and understanding that defining the relationship between our cells and our microbes has far reaching consequences that impact global health.

Embrace Creativity

To create cutting-edge technologies, pioneer scientific breakthroughs and develop new lines of biotherapeutics creativity is key. CMiST will provide an environment where creativity and innovation thrive to inspire its members and educate the community.


Cultivate Relationships

Cures begin with passion, but not one person can do it alone. Creating a dialogue between clinicians and scientists may seem like a no-brainer, but for two occupations working towards the same goal, sometimes it’s as if they are speaking different languages.  From our location on the UWMC campus and under the Department of Medicine, CMiST will provide a resource and a forum by which clinicians and scientists can share their work, their experiences and develop scientific relationships that will not only benefit one another, but also our patients.

Facilitate Discovery

To understand a complicated organ like the intestine and its microbial inhabitants a multidisciplinary team of investigators and cutting edge technologies is needed. CMiST will act as a catalyst to allow the exchange of ideas.

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Proud member of the following:



R. William DePaolo, PhD

Dr. William DePaolo, Will, Associate Professor of Medicine at the University of Washington Medical Center and recipient of the Lynn M. and Michael D. Garvey endowed chair in Gastroenterology, is Director of the Center for Microbiome Sciences & Therapeutics (CMiST). With Will at its helm, CMiST will serve as a beacon for investigators, clinicians and patients interested in the human microbiome, and will offer a number of Innovation Services, facilitate collaboration and exploration through workshops and seminar series, and work alongside clinicians to develop and test microbiome-derived therapeutics. 

In 2004, Will received his PhD in Immunology & Microbial Pathogenesis from the Feinberg School of Medicine of Northwestern University. Will then completed his postdoctoral training at the University of Chicago where he investigated the molecular pathogenesis of Yersinia pestis, the bacterium that causes bubonic plague, while concurrently developing projects investigating immune-modulation within the intestine. In 2011, Will joined the faculty at University of Southern California as an Assistant Professor in the Department of Molecular Microbiology and Immunology. Will combines his interdisciplinary training to investigate the contribution of our 100 trillion gut bacteria (or microbiome) to inflammatory diseases and to develop strategies aimed at manipulating this vast community. Will's current research extends across scientific disciplines and clinical diseases such as obesity, colon cancer, inflammatory bowel disease and enteric pathogens.


Our Partners


The Center for Innate Immunity and Immune Disease

CIIID is a scientific research center based at the University of Washington School of Medicine in Seattle, where researchers from diverse scientific backgrounds work together and focus their expertise to discover how innate immunity dictates the body’s response to infectious disease or impacts autoimmune disease.  For more information, visit their website here.


The Whole U

The Whole U launched in January 2014 to foster community, promote holistic wellness, and share the great perks available to UW faculty and staff. For more information, visit there website here.