The Center for Microbiome Sciences & Therapeutics (CMiST), part of the UW Medicine’s Department of Medicine, Division of Gastroenterology, is a scientific research center committed to understanding the dynamic interactions between the microbiome and our own human cells, to advancing the development of microbiome-based biotherapeutics to treat or prevent disease, and to educating the community about the importance of the microbiome in maintaining a healthy lifestyle. To accomplish these goals, CMiST has established relationships with world class clinicians, scientists, and educators that span biomedical and basic science departments as well as the arts.
With access to a brand new germ-free animal facility, services devoted to understanding host-microbial and microbial-microbial interactions, and an environment that promotes scientific rigor, fosters creativity, believes in the value of arts in science, and celebrates out-of-the-box thinking, CMiST will be a beacon for translational microbiome research.
E M B R A C E
C R E A T I V I T Y
To create cutting-edge technologies, pioneer scientific breakthroughs and develop new lines of biotherapeutics creativity is key. CMiST will provide an environment where creativity and innovation thrive to inspire its members and educate the community.
T H I N K
D E E P L Y
Too often the road with the least resistance is taken, but true innovation means looking past the obvious and not accepting answers at face value. Being able to think deeply means being open to all possibilities, thinking outside the box and understanding that defining the relationship between our cells and our microbes has far reaching consequences that impact global health.
C U L T I V A T E
R E L A T I O N S H I P S
Cures begin with passion, but not one person can do it alone. Creating a dialogue between clinicians and scientists may seem like a no-brainer, but for two occupations working towards the same goal, sometimes it’s as if they are speaking different languages.
From our location on the UWMC campus and under the Department of Medicine, CMiST will provide a resource and a forum by which clinicians and scientists can share their work, their experiences and develop scientific relationships that will not only benefit one another, but also our patients.
F A C I L I T A T E
D I S C O V E R Y
To understand a complicated organ like the intestine and its microbial inhabitants a multidisciplinary team of investigators and cutting edge technologies is needed. CMiST will act as a conduit to allow the exchange of ideas.
R. William DePaolo, PhD
Associate Professor | Medicine
Lynn M. & Michael D. Garvey Endowed Chair | Gastroenterology
Director | Center for Microbiome Sciences & Therapeutics (CMiST)
See the Press Kit to download bios, CV, head shot
American Society of Microbiology
American Association of Immunologists
Society for Mucosal Immunology
Dr. William DePaolo, Will, Associate Professor of Medicine at the University of Washington Medical Center and recipient of the Lynn M. and Michael D. Garvey endowed chair in Gastroenterology, is Director of the CMiST, Center for Microbiome Sciences & Therapeutics.
With Will at its helm, CMiST will serve as a beacon for investigators, clinicians and patients interested in the human microbiome, and will offer a number of services, facilitate collaboration and exploration through workshops and seminar series, and work alongside clinicians to develop and test microbiome-derived therapeutics.
In 2004, Will received his PhD in Immunology & Microbial Pathogenesis from the Feinberg School of Medicine of Northwestern University.
Will then completed his postdoctoral training at the University of Chicago where he investigated the molecular pathogenesis of Yersinia pestis, the bacterium that causes bubonic plague, while concurrently developing projects investigating immune-modulation within the intestine.
In 2011, Will joined the faculty at University of Southern California as an Assistant Professor in the Department of Molecular Microbiology and Immunology. Will combines his interdisciplinary training to investigate the contribution of our 100 trillion gut bacteria (or microbiome) to inflammatory diseases and to develop strategies aimed at manipulating this vast community.
Will's current research extends across scientific disciplines and clinical diseases such as obesity, colon cancer, inflammatory bowel disease and enteric pathogens.
“The purpose of this center is to work with clinicians and existing technologies and resources,” DePaolo says, citing the foresight of UW researchers to have stored so many samples as another factor that immediately impressed him about the University. “There’s a wealth of information saved away. [CMiST] is a place where we want all scientists to bring their research. I’m here to interface with the clinicians who don’t always have time to do research to start some projects focused on the gut and see if, from that, we can’t put together some interesting stories.”
— Will for The Whole U Friday Faculty, 2016
AIGA, The Professional Association for Design