Our Services

 

Experimental Consultation & Bioinformatics

Advice and information on starting a microbiome project or on how to use our technological resources and those of our affiliated centers and research groups to develop projects that test biological function

  • Review sequencing data and discuss microbes of interest
  • Bioinformatic analysis of your data sets (coming soon)
 

Clinical Microbiome Service

  • Microbiome cultivation of targeted species from stool or other samples
  • Inflammatory bowel disease microbiome biorepository of well-defined studies or patient groups that will allow longitudinal sampling and analysis of the same micorbiome species over the course of treatment, progression, or clinical trial

Equipment & Technologies
Bruker MALDI Biotyper
Shel Lab Bactron900 anaerobic chamber

 

Microbiome & Host Imaging

  • Isolate single cells, mucus layers or anatomical structures from histological samples
  • Determine spatial relationship between specific species of microbiome and host tissue 
  • Specific probes for microbial species

Equipment & Technologies
Leica laser capture microdissection microscope (LMD7000)
Leica fluorescent microscope (DM4)

 

Host-Microbiome Interactions

  • In vivo models: disease models
  • In vitro models: human and murine intestinal organoids, epithelial cells lines
  • Molecular and cellular immune assays
  • Screen potential therapeutics in any of these models

Equipment & Technologies
Human intestinal organoids for drug and bacterial screening
LICOR Odyssey Fc Imaging system
Gnotobiotic facility, affiliated resource through UW Gnotobiotic Animal Core (GNAC)
Luminex multiplex cytokine assays

 
 
 

Our service pipeline for stool samples